Research background · Updated November 1, 2026
MGF Research: Publications, Study Types and Background
Short answer
MGF. As of November 1, 2026, PubMed indexes 209 records matching MGF, the earliest from 1999; 18 were published in 2021–2025 and 28 are reviews. ClinicalTrials.gov lists 498 registered studies matching the compound.
- PubMed records
- 209
- Earliest record
- 1999
- Published 2021–2025
- 18
- Reviews
- 28
- Animal-only studies
- 71
- Registered studies
- 498
Publications per year, 2006–2025
69 records in 2016–2025 against 145 in 2006–2015; the busiest year was 2008, with 17.
See the numbers
| Year | PubMed records |
|---|---|
| 2006 | 9 |
| 2007 | 13 |
| 2008 | 17 |
| 2009 | 15 |
| 2010 | 15 |
| 2011 | 15 |
| 2012 | 16 |
| 2013 | 16 |
| 2014 | 15 |
| 2015 | 14 |
| 2016 | 10 |
| 2017 | 13 |
| 2018 | 10 |
| 2019 | 10 |
| 2020 | 6 |
| 2021 | 4 |
| 2022 | 6 |
| 2023 | 4 |
| 2024 | 4 |
| 2025 | 2 |
Study types
| All PubMed records | 209 |
|---|---|
| Reviews | 2813% |
| Animal studies (no human subjects indexed) | 7134% |
| Indexed as clinical trials | 73% |
| Registered on ClinicalTrials.gov | 498 |
Categories overlap and follow PubMed’s own indexing; recent records may not be indexed yet.
Primary research directions
What 2 of the most-cited and most recent MGF papers report, in their own authors’ terms. Each line links the paper it came from.
Tendon repair
In injured rat tendon, a synthetic mechano growth factor E peptide (MGF-C25E) was associated with healing, with histological evidence of tissue remodeling and cell alignment; the authors suggest it as a potential factor for tendon repair.
RatsZhang B 2016Biotechnology lettersPMID 27334712
Stem cell differentiation
In human bone marrow stromal cells under induction media, mechano growth factor enhanced differentiation while lowering the proliferation rate and lengthening the G1 phase of the cell cycle.
CellsLi H 2015Biotechnology lettersPMID 26330369
Most-studied topics
The Medical Subject Headings (MeSH) PubMed indexers most often marked as a main topic, across 209 of the 209 records. They describe what the literature is about, not what MGF does.
- Insulin-Like Growth Factor I130 papers
- Muscle, Skeletal57 papers
- Alternative Splicing12 papers
- Aging11 papers
- Cell Differentiation10 papers
- Mesenchymal Stem Cells10 papers
- Cell Proliferation10 papers
- Cell Movement10 papers
Key papers
Earliest indexed record
Goldspink G (1999). Journal of anatomy.
PMID 10386770Most-cited paper · 316 citations
De Bari C (2003). The Journal of cell biology.
PMID 12629053Most-cited #2 · 306 citations
Hameed M (2003). The Journal of physiology.
PMID 12562960Most-cited #3 · 296 citations
Goldspink G (1999). Journal of anatomy.
PMID 10386770
Citation counts from NIH iCite, among the 209 records sampled. Titles are left out; open each record on PubMed to read it.
Identity
| Identity data | On request |
|---|
Identity data from PubChem, retrieved November 1, 2026, on the MGF page.
How these numbers were counted
- PubMed search, run November 1, 2026:
"mechano growth factor"[tiab] OR "IGF-IEc"[tiab]re-run it. Study types add PubMed’s own filters (review, clinical trial, animals not humans). - Topics: MeSH major-topic headings counted across up to 400 of the matching records; headings for study set-up (species, sex, age) are left out.
- Citations: NIH iCite citation counts for the same records.
- ClinicalTrials.gov search:
"mechano growth factor"re-run it. Any phase, any status.
This page reports what has been published and what papers say they found, with each source linked. It gives no dosing or usage information, and nothing here is a reason to use MGF outside a laboratory.
Wholesale supply
MGF, sourced to order for research.
Not held in the listed catalog. Tell us the vial size and the number of vials and we come back with availability, documentation and pricing in writing.
MGF research questions
How much research has been published on MGF?
PubMed indexes 209 records matching MGF (searched November 1, 2026), including 28 reviews and 7 records indexed as clinical trials. 18 were published in the five years 2021–2025.
When was MGF first described in the literature?
The earliest PubMed record matching MGF is from 1999 (Goldspink G, Journal of anatomy, PMID 10386770).
What topics does the MGF literature cover?
The subject headings PubMed indexers most often marked as a main topic of MGF papers are Insulin-Like Growth Factor I, Muscle, Skeletal, Alternative Splicing, Aging. These describe what the literature is about. Findings from individual papers, with their sources, are summarized on this page.
Is MGF sold for human use?
No. Vanta Foundry supplies it for laboratory research use only. Not for human or veterinary use, and not a drug, food, cosmetic or dietary supplement.
Where can I buy MGF wholesale for research?
We source MGF to order rather than stock it. Tell us the vial size and number of vials on WhatsApp or by email and the quote confirms availability, documentation and pricing.
Research materials supplied by Vanta Foundry are for laboratory research use only. They are not for human or veterinary use and are not drugs, foods, cosmetics or dietary supplements. Websites and payment processing are business services for research-supply brands.
All compounds: research peptide publication statistics.