Research background · Updated November 1, 2026
Mazdutide Research: Publications, Study Types and Background
Short answer
Mazdutide. As of November 1, 2026, PubMed indexes 58 records matching Mazdutide, the earliest from 2021; 31 were published in 2021–2025 and 27 are reviews. ClinicalTrials.gov lists 46 registered studies matching the compound.
- PubMed records
- 58
- Earliest record
- 2021
- Published 2021–2025
- 31
- Reviews
- 27
- Animal-only studies
- 1
- Registered studies
- 46
Publications per year, 2006–2025
32 records in 2016–2025 against 0 in 2006–2015; the busiest year was 2025, with 20.
See the numbers
| Year | PubMed records |
|---|---|
| 2006 | 0 |
| 2007 | 0 |
| 2008 | 0 |
| 2009 | 0 |
| 2010 | 0 |
| 2011 | 0 |
| 2012 | 0 |
| 2013 | 0 |
| 2014 | 0 |
| 2015 | 0 |
| 2016 | 0 |
| 2017 | 0 |
| 2018 | 0 |
| 2019 | 0 |
| 2020 | 0 |
| 2021 | 1 |
| 2022 | 2 |
| 2023 | 1 |
| 2024 | 8 |
| 2025 | 20 |
Study types
| All PubMed records | 58 |
|---|---|
| Reviews | 2747% |
| Animal studies (no human subjects indexed) | 12% |
| Indexed as clinical trials | 1017% |
| Registered on ClinicalTrials.gov | 46 |
Categories overlap and follow PubMed’s own indexing; recent records may not be indexed yet.
Primary research directions
What 1 of the most-cited and most recent Mazdutide papers report, in their own authors’ terms. Each line links the paper it came from.
Body weight
In a 32-week phase 3 placebo-controlled trial of 610 Chinese adults with overweight or obesity, mean body weight changed by -14.0% in the higher mazdutide group against +0.3% with placebo; adverse events were mostly gastrointestinal and mild to moderate.
HumansJi L 2025The New England journal of medicinePMID 40421736
Most-studied topics
The Medical Subject Headings (MeSH) PubMed indexers most often marked as a main topic, across 58 of the 58 records. They describe what the literature is about, not what Mazdutide does.
- Obesity24 papers
- Diabetes Mellitus, Type 220 papers
- Glucagon-Like Peptide-1 Receptor Agonists14 papers
- Hypoglycemic Agents14 papers
- Anti-Obesity Agents10 papers
- Overweight9 papers
- Receptors, Glucagon6 papers
- Weight Loss6 papers
Key papers
Earliest indexed record
Ji L (2021). EClinicalMedicine.
PMID 34430840Most-cited paper · 99 citations
Ji L (2023). Nature communications.
PMID 38092790Most-cited #2 · 99 citations
Ji L (2025). The New England journal of medicine.
PMID 40421736Most-cited #3 · 80 citations
Zhang B (2024). Diabetes care.
PMID 37943529
Citation counts from NIH iCite, among the 58 records sampled. Titles are left out; open each record on PubMed to read it.
Identity
| CAS | 2259884-03-0 |
|---|---|
| Molecular formula | C207H317N45O65 |
| Molecular weight | 4476 g/mol |
| Synonyms | Mazdutide, IBI362, GTPL13924, IBI-362, GLXC-26803 |
Identity data from PubChem, retrieved November 1, 2026, on the Mazdutide page.
How these numbers were counted
- PubMed search, run November 1, 2026:
mazdutide[tiab] OR IBI362[tiab]re-run it. Study types add PubMed’s own filters (review, clinical trial, animals not humans). - Topics: MeSH major-topic headings counted across up to 400 of the matching records; headings for study set-up (species, sex, age) are left out.
- Citations: NIH iCite citation counts for the same records.
- ClinicalTrials.gov search:
mazdutidere-run it. Any phase, any status.
This page reports what has been published and what papers say they found, with each source linked. It gives no dosing or usage information, and nothing here is a reason to use Mazdutide outside a laboratory.
Wholesale supply
Mazdutide, sourced to order for research.
Not held in the listed catalog. Tell us the vial size and the number of vials and we come back with availability, documentation and pricing in writing.
Mazdutide research questions
How much research has been published on Mazdutide?
PubMed indexes 58 records matching Mazdutide (searched November 1, 2026), including 27 reviews and 10 records indexed as clinical trials. 31 were published in the five years 2021–2025.
When was Mazdutide first described in the literature?
The earliest PubMed record matching Mazdutide is from 2021 (Ji L, EClinicalMedicine, PMID 34430840).
What topics does the Mazdutide literature cover?
The subject headings PubMed indexers most often marked as a main topic of Mazdutide papers are Obesity, Diabetes Mellitus, Type 2, Glucagon-Like Peptide-1 Receptor Agonists, Hypoglycemic Agents. These describe what the literature is about. Findings from individual papers, with their sources, are summarized on this page.
Is Mazdutide sold for human use?
No. Vanta Foundry supplies it for laboratory research use only. Not for human or veterinary use, and not a drug, food, cosmetic or dietary supplement.
Where can I buy Mazdutide wholesale for research?
We source Mazdutide to order rather than stock it. Tell us the vial size and number of vials on WhatsApp or by email and the quote confirms availability, documentation and pricing.
Research materials supplied by Vanta Foundry are for laboratory research use only. They are not for human or veterinary use and are not drugs, foods, cosmetics or dietary supplements. Websites and payment processing are business services for research-supply brands.
All compounds: research peptide publication statistics.