Research background · Updated November 1, 2026
Ipamorelin Research: Publications, Study Types and Background
Short answer
Ipamorelin. As of November 1, 2026, PubMed indexes 51 records matching Ipamorelin, the earliest from 1998; 2 were published in 2021–2025 and 10 are reviews. ClinicalTrials.gov lists 3 registered studies matching the compound.
- PubMed records
- 51
- Earliest record
- 1998
- Published 2021–2025
- 2
- Reviews
- 10
- Animal-only studies
- 20
- Registered studies
- 3
Publications per year, 2006–2025
15 records in 2016–2025 against 13 in 2006–2015; the busiest year was 2016, with 4.
See the numbers
| Year | PubMed records |
|---|---|
| 2006 | 1 |
| 2007 | 0 |
| 2008 | 0 |
| 2009 | 2 |
| 2010 | 0 |
| 2011 | 1 |
| 2012 | 3 |
| 2013 | 1 |
| 2014 | 2 |
| 2015 | 3 |
| 2016 | 4 |
| 2017 | 2 |
| 2018 | 4 |
| 2019 | 1 |
| 2020 | 2 |
| 2021 | 0 |
| 2022 | 0 |
| 2023 | 0 |
| 2024 | 2 |
| 2025 | 0 |
Study types
| All PubMed records | 51 |
|---|---|
| Reviews | 1020% |
| Animal studies (no human subjects indexed) | 2039% |
| Indexed as clinical trials | 24% |
| Registered on ClinicalTrials.gov | 3 |
Categories overlap and follow PubMed’s own indexing; recent records may not be indexed yet.
Primary research directions
What 4 of the most-cited and most recent Ipamorelin papers report, in their own authors’ terms. Each line links the paper it came from.
Selective growth hormone release
This pharmacology paper reports that ipamorelin released growth hormone from rat pituitary cells and in rats and swine with potency and efficacy similar to GHRP-6, acting through a GHRP-like receptor; in swine it did not raise ACTH or cortisol beyond levels seen after GHRH, whereas GHRP-6 and GHRP-2 did.
AnimalsRaun K 1998European journal of endocrinologyPMID 9849822
Growth and bone
In adult female rats treated for 15 days, ipamorelin increased longitudinal bone growth rate and body weight gain without changing IGF-I, bone formation and resorption markers or pituitary GH content; the authors say clinical studies would be needed to judge any role in children with growth retardation.
RatsJohansen PB 1999Growth hormone & IGF researchPMID 10373343
Gastric emptying
In a rat model of surgery-induced delayed gastric emptying, ipamorelin accelerated emptying toward the level of non-surgical controls and reversed the reduced contractility of isolated gastric muscle, which the authors attribute to action on the ghrelin receptor.
RatsGreenwood-Van Meerveld B 2012Journal of experimental pharmacologyPMID 27186127
Postoperative ileus
In a rat model of postoperative ileus, a single intravenous ipamorelin treatment shortened the time to the first bowel movement and repeated treatment increased fecal output, food intake and body weight gain over 48 hours; the authors suggest it may ameliorate symptoms of postoperative ileus.
RatsVenkova K 2009The Journal of pharmacology and experimental therapeuticsPMID 19289567
Most-studied topics
The Medical Subject Headings (MeSH) PubMed indexers most often marked as a main topic, across 51 of the 51 records. They describe what the literature is about, not what Ipamorelin does.
- Growth Hormone13 papers
- Hormones12 papers
- Substance Abuse Detection9 papers
- Doping in Sports6 papers
- Performance-Enhancing Substances5 papers
- Growth Hormone-Releasing Hormone5 papers
- Dipeptides4 papers
- Receptors, Ghrelin4 papers
Key papers
Earliest indexed record
Hansen TK (1998). Journal of medicinal chemistry.
PMID 9733496Most-cited paper · 80 citations
Raun K (1998). European journal of endocrinology.
PMID 9849822Most-cited #2 · 74 citations
Thomas A (2011). Analytical and bioanalytical chemistry.
PMID 21298258Most-cited #3 · 58 citations
Lall S (2001). Biochemical and biophysical research communications.
PMID 11162489
Citation counts from NIH iCite, among the 51 records sampled. Titles are left out; open each record on PubMed to read it.
Identity
| CAS | 170851-70-4 |
|---|---|
| Molecular formula | C38H49N9O5 |
| Molecular weight | 711.9 g/mol |
| Synonyms | Ipamorelin, NNC-26-0161, Y9M3S784Z6, Aib-His-D-2-Nal-D-Phe-Lys-NH2, NNC-260161 |
Identity data from PubChem, retrieved November 1, 2026, on the Ipamorelin page.
How these numbers were counted
- PubMed search, run November 1, 2026:
ipamorelin[tiab]re-run it. Study types add PubMed’s own filters (review, clinical trial, animals not humans). - Topics: MeSH major-topic headings counted across up to 400 of the matching records; headings for study set-up (species, sex, age) are left out.
- Citations: NIH iCite citation counts for the same records.
- ClinicalTrials.gov search:
ipamorelinre-run it. Any phase, any status.
This page reports what has been published and what papers say they found, with each source linked. It gives no dosing or usage information, and nothing here is a reason to use Ipamorelin outside a laboratory.
Wholesale supply
Ipamorelin, sourced to order for research.
Not held in the listed catalog. Tell us the vial size and the number of vials and we come back with availability, documentation and pricing in writing.
Ipamorelin research questions
How much research has been published on Ipamorelin?
PubMed indexes 51 records matching Ipamorelin (searched November 1, 2026), including 10 reviews and 2 records indexed as clinical trials. 2 were published in the five years 2021–2025.
When was Ipamorelin first described in the literature?
The earliest PubMed record matching Ipamorelin is from 1998 (Hansen TK, Journal of medicinal chemistry, PMID 9733496).
What topics does the Ipamorelin literature cover?
The subject headings PubMed indexers most often marked as a main topic of Ipamorelin papers are Growth Hormone, Hormones, Substance Abuse Detection, Doping in Sports. These describe what the literature is about. Findings from individual papers, with their sources, are summarized on this page.
Is Ipamorelin sold for human use?
No. Vanta Foundry supplies it for laboratory research use only. Not for human or veterinary use, and not a drug, food, cosmetic or dietary supplement.
Where can I buy Ipamorelin wholesale for research?
We source Ipamorelin to order rather than stock it. Tell us the vial size and number of vials on WhatsApp or by email and the quote confirms availability, documentation and pricing.
Research materials supplied by Vanta Foundry are for laboratory research use only. They are not for human or veterinary use and are not drugs, foods, cosmetics or dietary supplements. Websites and payment processing are business services for research-supply brands.
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