Research background · Updated November 1, 2026
GHRP-6 Research: Publications, Study Types and Background
Short answer
GHRP-6. As of November 1, 2026, PubMed indexes 639 records matching GHRP-6, the earliest from 1988; 60 were published in 2021–2025 and 28 are reviews. ClinicalTrials.gov lists 0 registered studies matching the compound.
- PubMed records
- 639
- Earliest record
- 1988
- Published 2021–2025
- 60
- Reviews
- 28
- Animal-only studies
- 351
- Registered studies
- 0
Publications per year, 2006–2025
173 records in 2016–2025 against 296 in 2006–2015; the busiest year was 2011, with 42.
See the numbers
| Year | PubMed records |
|---|---|
| 2006 | 22 |
| 2007 | 28 |
| 2008 | 27 |
| 2009 | 23 |
| 2010 | 26 |
| 2011 | 42 |
| 2012 | 35 |
| 2013 | 30 |
| 2014 | 34 |
| 2015 | 29 |
| 2016 | 24 |
| 2017 | 22 |
| 2018 | 20 |
| 2019 | 24 |
| 2020 | 16 |
| 2021 | 19 |
| 2022 | 13 |
| 2023 | 11 |
| 2024 | 10 |
| 2025 | 14 |
Study types
| All PubMed records | 639 |
|---|---|
| Reviews | 284% |
| Animal studies (no human subjects indexed) | 35155% |
| Indexed as clinical trials | 427% |
| Registered on ClinicalTrials.gov | 0 |
Categories overlap and follow PubMed’s own indexing; recent records may not be indexed yet.
Primary research directions
What 2 of the most-cited and most recent GHRP-6 papers report, in their own authors’ terms. Each line links the paper it came from.
Growth hormone release
In experimental animal models and obese human subjects, GHRP-6 released growth hormone independently of the hypothalamic factors GHRH and somatostatin, and the authors describe it as a powerful GH releaser in obesity.
HumansMicic D 1993Journal of pediatric endocrinologyPMID 7920995
Mechanism of action
This review describes growth hormone-releasing peptides as synthetic peptides with potent GH-releasing activity acting at the pituitary and hypothalamic level, and notes that GHRP-6 was the first hexapeptide studied extensively in humans.
ReviewGhigo E 1997European journal of endocrinologyPMID 9186261
Most-studied topics
The Medical Subject Headings (MeSH) PubMed indexers most often marked as a main topic, across 400 of the 639 records. They describe what the literature is about, not what GHRP-6 does.
- Ghrelin130 papers
- Growth Hormone71 papers
- Receptors, Ghrelin62 papers
- Growth Hormone-Releasing Hormone62 papers
- Peptide Hormones35 papers
- Human Growth Hormone26 papers
- Neurons17 papers
- Hypothalamus16 papers
Key papers
Earliest indexed record
Chao CC (1988). Life sciences.
PMID 3123835Most-cited paper · 350 citations
Lawrence CB (2002). Endocrinology.
PMID 11751604Most-cited #2 · 282 citations
Smith RG (1993). Science (New York, N.Y.).
PMID 8503009Most-cited #3 · 279 citations
Hewson AK (2000). Journal of neuroendocrinology.
PMID 11069119
Citation counts from NIH iCite, among the 400 records sampled. Titles are left out; open each record on PubMed to read it.
Identity
| Molecular formula | C46H56N12O6 |
|---|---|
| Molecular weight | 873.0 g/mol |
| Synonyms | Ghrp-6, RefChem:201055, GHRP-2 Acetate, h-his-d-trp-ala-trp-d-phe-lys-nh2, orb341840 |
Identity data from PubChem, retrieved November 1, 2026, on the GHRP-6 page.
How these numbers were counted
- PubMed search, run November 1, 2026:
"GHRP-6"[tiab] OR "GHRP 6"[tiab]re-run it. Study types add PubMed’s own filters (review, clinical trial, animals not humans). - Topics: MeSH major-topic headings counted across up to 400 of the matching records; headings for study set-up (species, sex, age) are left out.
- Citations: NIH iCite citation counts for the same records.
- ClinicalTrials.gov search:
"GHRP-6"re-run it. Any phase, any status.
This page reports what has been published and what papers say they found, with each source linked. It gives no dosing or usage information, and nothing here is a reason to use GHRP-6 outside a laboratory.
Wholesale supply
GHRP-6, sourced to order for research.
Not held in the listed catalog. Tell us the vial size and the number of vials and we come back with availability, documentation and pricing in writing.
GHRP-6 research questions
How much research has been published on GHRP-6?
PubMed indexes 639 records matching GHRP-6 (searched November 1, 2026), including 28 reviews and 42 records indexed as clinical trials. 60 were published in the five years 2021–2025.
When was GHRP-6 first described in the literature?
The earliest PubMed record matching GHRP-6 is from 1988 (Chao CC, Life sciences, PMID 3123835).
What topics does the GHRP-6 literature cover?
The subject headings PubMed indexers most often marked as a main topic of GHRP-6 papers are Ghrelin, Growth Hormone, Receptors, Ghrelin, Growth Hormone-Releasing Hormone. These describe what the literature is about. Findings from individual papers, with their sources, are summarized on this page.
Is GHRP-6 sold for human use?
No. Vanta Foundry supplies it for laboratory research use only. Not for human or veterinary use, and not a drug, food, cosmetic or dietary supplement.
Where can I buy GHRP-6 wholesale for research?
We source GHRP-6 to order rather than stock it. Tell us the vial size and number of vials on WhatsApp or by email and the quote confirms availability, documentation and pricing.
Research materials supplied by Vanta Foundry are for laboratory research use only. They are not for human or veterinary use and are not drugs, foods, cosmetics or dietary supplements. Websites and payment processing are business services for research-supply brands.
All compounds: research peptide publication statistics.