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Vanta Foundry

How Peptide Blend Reports Work

Updated · Vanta Foundry

Short answer

How do you read a laboratory report for a peptide blend?

A blend report covers a vial that holds more than one peptide, so it has to answer two questions for each component: is it there, and how pure is it. Many blend reports give one average purity across all the components rather than a figure for each, so read which kind it is. Look for an identity result for every component on the label, and ask for per-component results if they matter to your work.

The Blend and Its Composition List

A blend is a single vial that contains two or more peptides, sold under one product name. The label should list every component and its labelled amount. Our blends class lists the blends in the Vanta catalog. Because several compounds share one vial, a single purity figure can't describe it the way it describes a single-compound product.

Start with the report's sample description. It should name each component, ideally with its labelled amount, and match the label on the vial. A report that names fewer components than the label, or a different compound, doesn't cover that blend. Check the lot number as you would for any report: the batch on the report should be the lot printed on the vials you'll receive.

Component Names Need the Same Care

Each name in a composition list should identify one compound. Some names in this category are used for more than one material, or come in versions with different identity data, such as a peptide with and without an attached chemical group. When a component name could mean more than one thing, ask the supplier which compound it is, in writing, and check that the identity result on the report matches it.

Where a name is ambiguous, our product pages say so rather than assert a sequence. CJC-1295 with DAC vs. without DAC shows how much one qualifier can change.

Labelled Amounts and the Total

A blend label usually gives both a total for the vial and an amount for each component, and the components should add up to the total. Our GLOW blend, for example, is listed as 70 mg in one vial: 10 mg of BPC-157, 10 mg of TB-500 (TB-4) and 50 mg of GHK-Cu, as shown on its product page. Check that the quote, the label and the report all use the same total and the same split.

If a label gives only a total, ask for the amount of each component in writing before you list the blend. A buyer reading your product page should see the full composition, not just a vial size.

Average vs. Per-Component Purity

In an HPLC run of a blend, each component produces its own main peak. A report can present the result in two ways. Neither is wrong, but they aren't interchangeable: when comparing blends from different suppliers, compare per-component figures with per-component figures, and averages with averages.

  • Per-component purity. A separate figure for each peptide, each with its own peak. This tells you how pure each compound is.
  • Average or combined purity. One figure across all the components. This is common on blend reports, but it can't show whether one component is purer than another.

A Worked Example

Take a hypothetical two-peptide blend; the figures are invented for illustration and come from no report. If one component measured a little higher than the other, an average across the two would sit between them. The average is a fair summary of the vial, but read alone it can't tell you which component sits above it and which below.

That is why the kind of figure matters when you compare blends. A per-component report from one supplier and an average from another can't be ranked against each other on a single number. Ask both for the same kind of result, or compare them on identity and documentation instead.

Identity for Each Component

Purity doesn't confirm identity. On a blend report, look for an identity result, usually by LC-MS, for each component: the observed mass beside the expected mass for every peptide on the label. If identity is reported for only one component, the others haven't been confirmed by that report.

Some multi-component products are documented with identity screens instead, which list the compounds detected in the vial but not how much of each is present. Read those as a check of what is there, not of amounts or purity.

Net Content on a Blend

When a blend report gives net content, it is usually one figure for the vial as a whole, set against the total labelled size, not an amount for each component. A total that matches the label doesn't show how it divides between the components.

If the split matters to your work, ask the supplier whether any per-component content was measured on the lot. HPLC purity vs. net peptide content explains how the two measures differ.

Single-Compound Reports Don't Cover a Blend

A report for a component sold on its own documents that vial, in that size, and nothing else. It doesn't document the same compound inside a blend, and a blend report doesn't document a single-compound vial. If you carry both, give each its own product page, SKU, label and report.

What to Ask For

Before you order a blend, ask the supplier for:

  • The report for the lot you'll receive, not a reference report for another batch or size.
  • Whether purity is per component or averaged.
  • An identity result for every component on the label.
  • Whether net content is for the vial as a whole or per component.
  • Whether any other tests were run on the lot, rather than inferring them from a purity figure.

Listing a Blend in Your Catalog

On your own product page, list every component and its labelled amount exactly as on the label, link the report for the lot you're selling, and say whether its purity figure is averaged. Describe the blend by what it contains, never by what it is for. If the vials carry your brand, the white label proof should show the full composition.

Getting the Report

Every wholesale lot from us comes with a certificate of analysis, and your quote names the lot you'll receive and its report. Published blend reports are in our COA library; see how to read a peptide COA for the rest of the document, and reference vs. batch-matched COAs for matching a report to your lot. To get a quote, add the blend to your list in the catalog.

Common questions

Why does my blend report show only one purity figure?
Many blend reports give an average purity across all the components. It describes the blend as a whole, not each peptide in it.
Does a report for each single peptide cover a blend?
No. A report covers the sample tested. A blend needs a report for the blend, from the lot you'll receive.
Should a blend report confirm the identity of every component?
Look for an identity result for each component on the label. If only one is confirmed, the others haven't been confirmed by that report.
Is net content on a blend given per component?
Usually it is one figure for the vial as a whole. Ask the supplier whether any per-component content was measured on the lot.
Can I compare an average purity with a per-component figure?
Not directly. Compare averages with averages and per-component results with per-component results.

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